Subtelomeric Transcription and its Regulation

Down Regulation of DHFR Promoter Activity by PML Transcription Repressor

Cryptic Transcription Mediates Repression of Subtelomeric Metal Homeostasis Genes

Nonsense-mediated mRNA decay (NMD) prevents the accumulation of transcripts bearing premature termination codons. Here we show that Saccharomyces cerevisiae NMD mutants accumulate 5'-extended RNAs (CD-CUTs) of many subtelomeric genes. Using the subtelomeric ZRT1 and FIT3 genes activated in response to zinc and iron deficiency, respectively, we show that transcription of these CD-CUTs mediates r...

The NF-kB Family of Transcription Factors and Its Regulation

References http://cshperspectives.cshlp.org/content/1/4/a000034.full.html#ref-list-1 This article cites 106 articles, 45 of which can be accessed free service Email alerting click here box at the top right corner of the article or Receive free email alerts when new articles cite this article sign up in the Subject collections (16 articles) NF-κB • Articles on similar topics can be found i...

Optogenetic regulation of site-specific subtelomeric DNA-methylation

Telomere length homeostasis, critical for chromosomal integrity and genome stability, is controlled by intricate molecular regulatory machinery that includes epigenetic modifications. Here, we examine site-specific and spatiotemporal alteration of the subtelomeric methylation of CpG islands using optogenetic tools to understand the epigenetic regulatory mechanisms of telomere length maintenance...

down regulation of dhfr promoter activity by pml transcription repressor

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